中國人胃癌的預(yù)后因素-石元凱 內(nèi)容預(yù)覽:
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中國人胃癌的預(yù)后因素-石元凱 內(nèi)容簡介:
ClinicalPrognosticFactorsinGastricCancerinChinesePatients:
ExperiencefromtheCancerHospital/Institute,
ChineseAcademyofMedicalSciences
YuankaiShi,M.D.
DepartmentofMedicalOncology,
CancerHospital/Institute,
ChineseAcademyofMedicalSciences(CAMS)
Background
Gastriccancerworldwidein2002:
4thmostcommoncancer,2ndmostcommoncauseofdeath,
2/3patientsindevelopingcountries,42%oftheminChina
ParkinDM,etal.CACancerJClin.2005;55:74
5-yearoverallsurvival:15%-54%
ParkinDM,etal.CACancerJClin.2005;55:74
GastriccancerinChinain2005
Incidence:
376,000newcases
Thirdmostcommoncancer
Mortality:
24.71/105
Thirdcauseofdeathfromcancer
BehindLungcancerandLivercancer
http://www.moh.gov.cn
Objective
Toevaluatethetherapeuticeffectsandprognosticfactorsinpatientswithoperablegastriccancer
Toconstructaprognosticmodel
aterialsandmethods
Identifyprognosticfactorswithdatafrom1043ptstreatedwithcombinedmodalitytherapybasedongastrectomy,between1999and2002,intheCancerHospital,CAMS
Constructprognosticmodelwithdatafrom1284ptswithcombinedmodalitytreatmentbasedongastrectomy,between1999-2006,intheCancerHospital,CAMS
Statistical**ysis
LifeTable,Coxhazardproportionalmodel,Logisticregressionmodel
Results
5-year
39%
15%
1043ptswithoperablegastriccancer
Mediansurvival:39.5mo
medianrelapse-freesurvival:22.7mo
5-yOS:39%
5-yRFS:15%
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