《DIC彌漫性血管內(nèi)凝血-北京協(xié)和醫(yī)院血液科》專家PPT內(nèi)容預(yù)覽
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《DIC彌漫性血管內(nèi)凝血-北京協(xié)和醫(yī)院血液科》專家PPT內(nèi)容簡介
Disseminated Intravascular Coagulation
DIC是一種發(fā)生于多種疾病或特殊病理狀態(tài)下,人體凝血系統(tǒng)被激活而引起中小血管內(nèi)彌漫性微血栓形成及繼發(fā)性纖溶亢進的綜合征。
由于DIC發(fā)展過程中出現(xiàn)不同程度的血小板和凝血因子水平消耗性減少,也稱之為“消耗性凝血病”或“消耗性血栓出血性疾病”。
Clinical conditions associated with DIC
1. Sepsis/Severe infection --- -------- 44.6%
2. Malignancy ------------------------- 20.7%
Solid tumors 6.9%,AL 13.8%. Occurrence in APL 37~65%.
3. Obstetrical calamities ------------ 13.4%
Amniotic fluid embolism, Abruptio placentae, Dead fetus
4. Trauma / Surgery ----------------- 7.4%
5. Severe hepatic failure ------------ 7.4%
6. Vascular abnormalities
Kasabach-Merritt syndrome,Large vascular aneurysms
7. Organ destruction (e.g., severe pancreatitis)
8. Severe toxic or immunologic reactions
Snake bites,Recreational drugs,Transfusion reactions,Transplant rejection
Mortality
DIC----Death Is Coming.
Mortality ranges from 31~86%, whether or not heparin was administrated.
Correlated Factors:
Underlying disorders
The extent of orgon dysfuction
The degree of hemostatic failure
Increasing age
《DIC彌漫性血管內(nèi)凝血-北京協(xié)和醫(yī)院血液科》專家PPT完整版下載地址:
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